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List of all Dr. Sigmund's publications on PubMed.

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2009  2008  2007  2006  2005   2004   2003   2002   2001   2000   1999-1996   1995-1991   1990 and earlier


2011 Publications:

Inflaming hypothalamic neurons raises blood pressure.
Rahmouni K, Davisson RL, Sigmund CD.
Cell Metab. 2011 Jul 6;14(1):3-4.
PMID: 21723497 [PubMed - in process] 

Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation.
Harlan SM, Morgan DA, Agassandian K, Guo DF, Cassell MD, Sigmund CD, Mark AL, Rahmouni K.
Circ Res. 2011 Apr 1;108(7):808-12. Epub 2011 Feb 10.
PMID: 21311043 [PubMed - indexed for MEDLINE] 

Cystic fibrosis transmembrane conductance regulator with a shortened R domain rescues the intestinal phenotype of CFTR-/- mice.
Ostedgaard LS, Meyerholz DK, Vermeer DW, Karp PH, Schneider L, Sigmund CD, Welsh MJ.
Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2921-6. Epub 2011 Feb 1.
PMID: 21285372 [PubMed - indexed for MEDLINE] 

Angiotensinergic signaling in the brain mediates metabolic effects of deoxycorticosterone (DOCA)-salt in C57 mice.
Grobe JL, Buehrer BA, Hilzendeger AM, Liu X, Davis DR, Xu D, Sigmund CD.
Hypertension. 2011 Mar;57(3):600-7. Epub 2011 Jan 24.
PMID: 21263123 [PubMed - indexed for MEDLINE] 

Neuron- or glial-specific ablation of secreted renin does not affect renal renin, baseline arterial pressure, or metabolism.
Xu D, Borges GR, Davis DR, Agassandian K, Sequeira Lopez ML, Gomez RA, Cassell MD, Grobe JL, Sigmund CD.
Physiol Genomics. 2011 Mar 29;43(6):286-94. Epub 2010 Dec 28.
PMID: 21189370 [PubMed - in process] 


2010 Publications:

Structural biology: On stress and pressure.
Sigmund CD.
Nature. 2010 Nov 4;468(7320):46-7. No abstract available. 
PMID: 21048758 [PubMed - indexed for MEDLINE] 

The brain Renin-angiotensin system controls divergent efferent mechanisms to regulate fluid and energy balance.
Grobe JL, Grobe CL, Beltz TG, Westphal SG, Morgan DA, Xu D, de Lange WJ, Li H, Sakai K, Thedens DR, Cassis LA, Rahmouni K, Mark AL, Johnson AK, Sigmund CD.
Cell Metab. 2010 Nov 3;12(5):431-42.
PMID: 21035755 [PubMed - indexed for MEDLINE] 

Cardiovascular consequences of genetic variation at -6/235 in human angiotensinogen using "humanized" gene-targeted mice.
Grobe JL, Dickson ME, Park S, Davis DR, Born EJ, Sigmund CD.
Hypertension. 2010 Nov;56(5):981-7. Epub 2010 Sep 7.
PMID:20823378 [PubMed - indexed for MEDLINE] 

Transgenic mice expressing an intracellular fluorescent fusion of angiotensin II demonstrate renal thrombotic microangiopathy and elevated blood pressure.
Redding KM, Chen BL, Singh A, Re RN, Navar LG, Seth DM, Sigmund CD, Tang WW, Cook JL.
Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H1807-18. Epub 2010 Apr 2.
PMID: 20363893 [PubMed - indexed for MEDLINE] 

Twists and turns in the search for the elusive renin processing enzyme: focus on "Cathepsin B is not the processing enzyme for mouse prorenin".
Gross KW, Gomez RA, Sigmund CD.
Am J Physiol Regul Integr Comp Physiol. 2010 May;298(5):R1209-11. Epub 2010 Mar 17. No abstract available. 
20237305 [PubMed - indexed for MEDLINE] 
Does peroxisome proliferator-activated receptor-gamma (PPAR gamma) protect from hypertension directly through effects in the vasculature?
Ketsawatsomkron P, Pelham CJ, Groh S, Keen HL, Faraci FM, Sigmund CD.
J Biol Chem. 2010 Mar 26;285(13):9311-6. Epub 2010 Feb 3. Review.
PMID: 20129921 [PubMed - indexed for MEDLINE] 

Increased Renin Production in Mice With Deletion of Peroxisome Proliferator-Activated Receptor-{gamma} in Juxtaglomerular Cells.

Desch M, Schreiber A, Schweda F, Madsen K, Friis UG, Weatherford ET, Sigmund CD, Sequeira Lopez ML, Gomez RA, Todorov VT.

Hypertension. 2010;55:660-666.

PMID: 20065157


The MicroRNA-Processing Enzyme Dicer Maintains Juxtaglomerular Cells.

Sequeira-Lopez ML, Weatherford ET, Borges GR, Monteagudo MC, Pentz ES, Harfe BD, Carretero O, Sigmund CD, Gomez RA.

J Am Soc Nephrol. 2010;21:460-467.

PMID: 20056748

PMCID: PMC2831866



Bioinformatic Analysis of Gene Sets Regulated by Ligand-Activated and Dominant-Negative Peroxisome Proliferator-Activated Receptor {gamma} in Mouse Aorta.

Keen HL, Halabi CM, Beyer AM, de Lange WJ, Liu X, Maeda N, Faraci FM, Casavant TL, Sigmund CD.

Arterioscler Thromb Vasc Biol. 2010;30:518-525.

PMID: 20018933


Brain-Selective Overexpression of Human Angiotensin-Converting Enzyme Type 2 Attenuates Neurogenic Hypertension.

Feng Y, Xia H, Cai Y, Halabi CM, Becker LK, Santos RA, Speth RC, Sigmund CD, Lazartigues E.

Circ Res. 2010;106:373-382.

PMID: 19926873

PMCID: PMC2818798


Team exercise.

Sigmund CD.

Am J Physiol Regul Integr Comp Physiol. 2010;298:R1.

PMID: 19923356



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