2008

1: Sigmund CD.

A growing chain of evidence linking genetic variation in angiotensinogen with essential hypertension: focus on "A haplotype of human angiotensinogen gene containing -217A increases blood pressure in transgenic mice compared with -217G," by Jain et al.

Am J Physiol Regul Integr Comp Physiol. 2008 Dec;295(6):R1846-8.

PMID: 18971347

2: Harlan SM, Reiter RS, Sigmund CD, Lin JL, Lin JJ.

Requirement of TCTG(G/C) Direct Repeats and Overlapping GATA Site for Maintaining the Cardiac-Specific Expression of Cardiac troponin T in Developing and Adult Mice.

Anatomical Record. 2008 Dec;291(12):1574-86.

PMID: 18951515

PMCID: PMC2592506

3: Dickson ME, Tian X, Liu X, Davis DR, Sigmund CD.

Upstream stimulatory factor is required for human angiotensinogen expression and differential regulation by the A-20C polymorphism.

Circulation Research 2008 Oct 24;103(9):940-7.

PMID: 18802024

PMCID: PMC2678906

4: Rahmouni K, Sigmund CD.

Id3, E47, and SREBP-1c: fat factors controlling adiponectin expression.

Circulation Research. 2008 Sep 12;103(6):565-7. Review.

PMID: 18796641

PMCID: PMC2728444

5: Grobe JL, Xu D, Sigmund CD.

An intracellular renin-angiotensin system in neurons: fact, hypothesis, or fantasy.

Physiology (Bethesda). 2008 Aug;23:187-93. Review.

PMID: 18697992

PMCID: PMC2538674

6: Beyer AM, de Lange WJ, Halabi CM, Modrick ML, Keen HL, Faraci FM, Sigmund CD.

Endothelium-specific interference with peroxisome proliferator activated receptor gamma causes cerebral vascular dysfunction in response to a high-fat diet.

Circulation Research . 2008 Sep 12;103(6):654-61.

PMID: 18676352

PMCID: PMC2583077

7: Zhou X, Weatherford ET, Liu X, Born E, Keen HL, Sigmund CD.

Dysregulated human renin expression in transgenic mice carrying truncated genomic constructs: evidence supporting the presence of insulators at the renin locus.

Am J Physiol Renal Physiol. 2008 Sep;295(3):F642-53.

PMID: 18632798

PMCID: PMC2536869

8: de Lange WJ, Halabi CM, Beyer AM, Sigmund CD.

Germ line activation of the Tie2 and SMMHC promoters causes noncell-specific deletion of floxed alleles.

Physiological Genomics. 2008 Sep 17;35(1):1-4.

PMID: 18612081

PMCID: PMC2574738

9: Shi PP, Cao XR, Sweezer EM, Kinney TS, Williams NR, Husted RF, Nair R, Weiss RM, Williamson RA, Sigmund CD, Snyder PM, Staub O, Stokes JB, Yang B.

Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2.

Am J Physiol Renal Physiol. 2008 Aug;295(2):F462-70.

PMID: 18524855

PMCID: PMC2519178

10: Li H, Zhou X, Davis DR, Xu D, Sigmund CD.

An androgen-inducible proximal tubule-specific Cre recombinase transgenic model.

Am J Physiol Renal Physiol. 2008 Jun;294(6):F1481-6.

PMID: 18385272

11: Halabi CM, Beyer AM, de Lange WJ, Keen HL, Baumbach GL, Faraci FM, Sigmund CD.

Interference with PPAR gamma function in smooth muscle causes vascular dysfunction and hypertension.

Cell Metabolism. 2008 Mar;7(3):215-26.

PMID: 18316027

PMCID: PMC2275166

12: Wakisaka Y, Miller JD, Chu Y, Baumbach GL, Wilson S, Faraci FM, Sigmund CD, Heistad DD.

Oxidative stress through activation of NAD(P)H oxidase in hypertensive mice with spontaneous intracranial hemorrhage.

J Cereb Blood Flow Metab. 2008 Jun;28(6):1175-85.

PMID: 18301433

13: Beyer AM, Baumbach GL, Halabi CM, Modrick ML, Lynch CM, Gerhold TD, Ghoneim SM, de Lange WJ, Keen HL, Tsai YS, Maeda N, Sigmund CD, Faraci FM.

Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling.

Hypertension. 2008 Apr;51(4):867-71.

PMID: 18285614

PMCID: PMC2408877

14: Zhou X, Sigmund CD.

Chorionic enhancer is dispensable for regulated expression of the human renin gene.

Am J Physiol Regul Integr Comp Physiol. 2008 Feb;294(2):R279-87.

PMID: 18077515

PMCID: PMC2408876