2006 Publications:

1: Sinnayah P, Lazartigues E, Sakai K, Sharma RV, Sigmund CD, Davisson RL.  
  Genetic ablation of angiotensinogen in the subfornical organ of the brain prevents the central angiotensinergic pressor response.
Circulation Research. 2006 Nov 10;99(10):1125-31.
PMID: 17053195
2: Zhou X, Davis DR, Sigmund CD.  
  The human renin kidney enhancer is required to maintain base-line renin expression but is dispensable for tissue-specific, cell-specific, and regulated expression.
J Biological Chemistry. 2006 Nov 17;281(46):35296-304.
PMID: 16990260
3: Liu X, Shi Q, Sigmund CD.  
  Interleukin-1beta attenuates renin gene expression via a mitogen-activated protein kinase kinase-extracellular signal-regulated kinase and signal transducer and activator of transcription 3-dependent mechanism in As4.1 cells.
Endocrinology. 2006 Dec;147(12):6011-8.
PMID: 16959849
4: Dickson ME, Sigmund CD.  
  Genetic basis of hypertension: revisiting angiotensinogen.
Hypertension. 2006 Jul;48(1):14-20.
PMID: 16754793
5: Brand M, Lamande N, Sigmund CD, Larger E, Corvol P, Gasc JM.  
  Angiotensinogen modulates renal vasculature growth.
Hypertension. 2006 Jun;47(6):1067-74.
PMID: 16636191
6: Cao XR, Shi PP, Sigmund RD, Husted RF, Sigmund CD, Williamson RA, Stokes JB, Yang B.  
  Mice heterozygous for beta-ENaC deletion have defective potassium excretion.
Am J Physiol Renal Physiol. 2006 Jul;291(1):F107-15.
PMID: 16571596
7: Sachetelli S, Liu Q, Zhang SL, Liu F, Hsieh TJ, Brezniceanu ML, Guo DF, Filep JG, Ingelfinger JR, Sigmund CD, Hamet P, Chan JS.  
  RAS blockade decreases blood pressure and proteinuria in transgenic mice overexpressing rat angiotensinogen gene in the kidney.
Kidney International. 2006 Mar;69(6):1016-23.
PMID: 16528251
8: Sethi S, Iida S, Sigmund CD, Heistad DD.  
  Renal thrombotic microangiopathy in a genetic model of hypertension in mice.
Exp Biol Med (Maywood). 2006 Feb;231(2):196-203.
PMID: 16446496
9: Lavoie JL, Liu X, Bianco RA, Beltz TG, Johnson AK, Sigmund CD.  
  Evidence supporting a functional role for intracellular renin in the brain.
Hypertension. 2006 Mar;47(3):461-6. Epub 2006 Jan 30.
PMID: 16446393
10: Kiss PJ, Knisz J, Zhang Y, Baltrusaitis J, Sigmund CD, Thalmann R, Smith RJ, Verpy E, Banfi B.  
  Inactivation of NADPH oxidase organizer 1 results in severe imbalance.
Current Biology. 2006 Jan 24;16(2):208-13.
PMID: 16431374