Smith Antibody
Label Mnemonic: SM
Epic Lab Code: LAB1250
Downtime Form: A-1a General Laboratory Requisition
Chemistry
6240 RCP
356-3527
Specimen(s):
Plasma
Collection Medium:
Plasma Separator Tube 4.5 mL
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
3.0 mL whole blood from light green top tube or TWO Microtainer® devices
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
3 hours (upon receipt in laboratory)
Reference Range:
1.0 AI (antibody index) or less
Interpretive Data:
Smith (Sm) antibodies are specific for lupus erythematosus (LE) and occur in approximately 30% of LE patients. Levels of Sm antibodies remain relatively constant over time in patient with LE and are typically found in patients that also have RNP antibodies.
Comments:
Assay methodology and reference ranges changed February 25, 2013.
Methodology:
Multiplex flow immunoassay
CPT Code:
86235