Jo-1 Antibody
Label Mnemonic: JO1
Epic Lab Code: LAB3455
Downtime Form: A-1a General Laboratory Requisition
Chemistry
6240 RCP
356-3527
Specimen(s):
Plasma
Collection Medium:
Plasma Separator Tube 4.5 mL
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
3.0 mL whole blood from light green top tube or TWO Microtainer® devices
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
3 hours (upon receipt in laboratory)
Reference Range:
1.0 AI (antibody index) or less
Interpretive Data:
Jo-1 antibodies are a marker for polymyositis and occur most commonly in myositis patients with interstitial lung disease. Jo-1 antibodies occur in 50% or more of patient with interstitial pulmonary fibrosis and symmetrical polyarthritis. A negative result for Jo-1 antibodies does not rule out polymyositis.
Comments:
Assay methodology and reference ranges changed February 25, 2013.
Methodology:
Multiplex flow immunoassay
CPT Code:
86235