PM-Scl (PM1) Antibody, IgG
| Label Mnemonic: | PM100 |
| Epic code: | LAB7440 |
| Downtime form: | Doctor/Provider Orders - Pathology Core and Specialty Care Nursery |
Commercial Mailout Laboratory
6240-8 RCP
356-8593
6240-8 RCP
356-8593
Specimen(s):
Serum
Collection Medium:
 |
| Red top tube 5 mL (Clot Activator) |
Minimum:
Preferred Minimum: 1 mL serum
Rejection Criteria:
Plasma. Contaminated, hemolyzed, or severely lipemic specimens.
Turn Around
Time:
1-4 days upon receipt at reference laboratory.
Reference Range:
Negative
Interpretive Data:
The presence of PM/Scl-100 IgG antibody along with a positive ANA IFA
nucleolar pattern is associated with connective tissue diseases such
as polymyositis (PM), dermatomyositis (DM), systemic sclerosis (SSc),
and polymyositis/systemic sclerosis overlap syndrome. The clinical
relevance of PM/Scl-100 IgG antibody with a negative ANA IFA nucleolar
pattern is unknown. PM/Scl-100 is the main target epitope of the
PM/Scl complex, although antibodies to other targets not detected by
this assay may occur.
Methodology:
Qualitative Immunoblot
CPT Code:
86235