Ribosomal P Protein
Label Mnemonic: RIBOP
Epic Lab Code: LAB3995
Downtime Form: A-1a General Laboratory Requisition
Chemistry
6240 RCP
356-3527
Specimen(s):
Plasma
Collection Medium:
Plasma Separator Tube 4.5 mL
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
3.0 mL whole blood from light green top tube or TWO Microtainer® devices
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
3 hours (upon receipt in laboratory)
Reference Range:
1.0 AI (antibody index) or less
Interpretive Data:
Ribosomal P antibodies are primarily used as an adjunct in the evaluation of patients with suspected lupus erythematosus (LE). Antibodies to ribosome P proteins are considered highly specific to LE and have been reported in patients with central nervous system involvement. The frequency of ribosomal P antibodies in patients with LE is approximately 12%. A negative result for ribosomal P antibodies does not rule out LE.
Comments:
Assay methodology and reference ranges changed February 25, 2013.
Methodology:
Multiplex flow immunoassay
CPT Code:
86235