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Publications

2005-present

  1. Herrmann TL, Morita CT, Lee K, Kusner DJ. Calmodulin kinase II regulates the maturation and antigen presentation of human dendritic cells. J Leukoc Biol. 2005 Dec;78(6):1397-407. Click here to download.

  2. Puan KJ, Wang H, Dairi T, Kuzuyama T, Morita CT. fldA is an essential gene required in the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis. FEBS Lett. 2005 Jul 4;579(17):3802-6. Click here to download.

  3. Sanders JM, Song Y, Chan JM, Zhang Y, Jennings S, Kosztowski T, Odeh S, Flessner R, Schwerdtfeger C, Kotsikorou E, Meints GA, Gomez AO, Gonzalez-Pacanowska D, Raker AM, Wang H, van Beek ER, Papapoulos SE, Morita CT, Oldfield E. Pyridinium-1-yl bisphosphonates are potent inhibitors of farnesyl diphosphate synthase and bone resorption. J Med Chem. 2005 Apr 21;48(8):2957-63. Click here to download.

  4. Wouters J, Yin F, Song Y, Zhang Y, Oudjama Y, Stalon V, Droogmans L, Morita CT, Oldfield E. A crystallographic investigation of phosphoantigen binding to isopentenyl pyrophosphate/dimethylallyl pyrophosphate isomerase. J Am Chem Soc. 2005 Jan 19;127(2):536-7.Click here to download.

2000-2004

  1. Xiong X, Morita CT, Bukowski JF, Brenner MB, Dascher CC. Identification of guinea pig γδ T cells and characterization during pulmonary tuberculosis. Vet Immunol Immunopathol. 2004 Nov;102(1-2):33-44.Click here to download.

  2. Song Y, Zhang Y, Wang H, Raker AM, Sanders JM, Broderick E, Clark A, Morita CT, Oldfield E. Synthesis of chiral phosphoantigens and their activity in γδ T cell stimulation. Bioorg Med Chem Lett. 2004 Sep 6;14(17):4471-7. Click here to download.

  3. Sanders JM, Ghosh S, Chan JM, Meints G, Wang H, Raker AM, Song Y, Colantino A, Burzynska A, Kafarski P, Morita CT, Oldfield E. Quantitative structure-activity relationships for γδ T cell activation by bisphosphonates. J Med Chem. 2004 Jan 15;47(2):375-84. Click here to download.

  4. Brandes M, Willimann K, Lang AB, Nam KH, Jin C, Brenner MB, Morita CT, Moser B. Flexible migration program regulates γδ T-cell involvement in humoral immunity. Blood. 2003 Nov 15;102(10):3693-701. Click here to download. Supplemental Data.

  5. Wang H, Lee HK, Bukowski JF, Li H, Mariuzza RA, Chen ZW, Nam KH, Morita CT. Conservation of nonpeptide antigen recognition by rhesus monkey Vg2V d2 T cells. J Immunol. 2003 Apr 1;170(7):3696-706. Click here to download.

  6. Leslie DS, Vincent MS, Spada FM, Das H, Sugita M, Morita CT, Brenner MB. CD1-mediated γδ T cell maturation of dendritic cells. J Exp Med. 2002 Dec 16;196(12):1575-84. Click here to download.

  7. Shen Y, Zhou D, Qiu L, Lai X, Simon M, Shen L, Kou Z, Wang Q, Jiang L, Estep J, Hunt R, Clagett M, Sehgal PK, Li Y, Zeng X, Morita CT, Brenner MB, Letvin NL, Chen ZW. Adaptive immune response of Vg2Vd2+ T cells during mycobacterial infections. Science. 2002 Mar 22;295(5563):2255-8. Click here to download.

  8. Das H, Groh V, Kuijl C, Sugita M, Morita CT, Spies T, Bukowski JF. MICA engagement by human V g2V d2 T cells enhances their antigen-dependent effector function. Immunity. 2001 Jul;15(1):83-93. Click here to download.

  9. Morita CT, Lee HK, Wang H, Li H, Mariuzza RA, Tanaka Y. Structural features of nonpeptide prenyl pyrophosphates that determine their antigenicity for human γδ T cells. J Immunol. 2001 Jul 1;167(1):36-41. Click here to download.

  10. Morita CT, Li H, Lamphear JG, Rich RR, Fraser JD, Mariuzza RA, Lee HK. Superantigen recognition by γδ T cells: SEA recognition site for human Vg2 T cell receptors. Immunity. 2001 Mar;14(3):331-44. Click here to download.

  11. Bukowski JF, Roncarolo MG, Spits H, Krangel MS, Morita CT, Brenner MB, Band H. T cell receptor-dependent activation of human lymphocytes through cell surface ganglioside GT1b: implications for innate immunity. Eur J Immunol. 2000 Nov;30(11):3199-206. Click here to download.

  12. Spada FM, Grant EP, Peters PJ, Sugita M, Melian A, Leslie DS, Lee HK, van Donselaar E, Hanson DA, Krensky AM, Majdic O, Porcelli SA, Morita CT, Brenner MB. Self-recognition of CD1 by γδ T cells: implications for innate immunity. J Exp Med. 2000 Mar 20;191(6):937-48. Click here to download.

1990-1999

  1. Bukowski JF, Morita CT, Brenner MB. Human γδ T cells recognize alkylamines derived from microbes, edible plants, and tea: implications for innate immunity. Immunity. 1999 Jul;11(1):57-65. Click here to download.

  2. Garcia VE, Uyemura K, Sieling PA, Ochoa MT, Morita CT, Okamura H, Kurimoto M, Rea TH, Modlin RL. IL-18 promotes type 1 cytokine production from NK cells and T cells in human intracellular infection. J Immunol. 1999 May 15;162(10):6114-21. Click here to download.

  3. Bukowski JF, Morita CT, Band H, Brenner MB. Crucial role of TCR g chain junctional region in prenyl pyrophosphate antigen recognition by γδ T cells. J Immunol. 1998 Jul 1;161(1):286-93. Click here to download.

  4. Garcia VE, Jullien D, Song M, Uyemura K, Shuai K, Morita CT, Modlin RL. IL-15 enhances the response of human γδ T cells to nonpeptide [correction of nonpetide] microbial antigens. J Immunol. 1998 May 1;160(9):4322-9. Click here to download.

  5. Roth SJ, Diacovo TG, Brenner MB, Rosat JP, Buccola J, Morita CT, Springer TA. Transendothelial chemotaxis of human ab and γδ T lymphocytes to chemokines. Eur J Immunol. 1998 Jan;28(1):104-13. Click here to download.

  6. Garcia VE, Sieling PA, Gong J, Barnes PF, Uyemura K, Tanaka Y, Bloom BR, Morita CT, Modlin RL. Single-cell cytokine analysis of γδ T cell responses to nonpeptide mycobacterial antigens. J Immunol. 1997 Aug 1;159(3):1328-35. Click here to download.

  7. Diacovo TG, Roth SJ, Morita CT, Rosat JP, Brenner MB, Springer TA. Interactions of human ab and γδ T lymphocyte subsets in shear flow with E-selectin and P-selectin. J Exp Med. 1996 Mar 1;183(3):1193-203. Click here to download.

  8. Morita CT, Beckman EM, Bukowski JF, Tanaka Y, Band H, Bloom BR, Golan DE, Brenner MB. Direct presentation of nonpeptide prenyl pyrophosphate antigens to human γδ T cells. Immunity. 1995 Oct;3(4):495-507. Click here to download.

  9. Tanaka Y, Morita CT, Tanaka Y, Nieves E, Brenner MB, Bloom BR. Natural and synthetic non-peptide antigens recognized by human γδ T cells. Nature. 1995 May 11;375(6527):155-8. Click here to download.

  10. Bukowski JF, Morita CT, Tanaka Y, Bloom BR, Brenner MB, Band H. Vg2Vd2 TCR-dependent recognition of non-peptide antigens and Daudi cells analyzed by TCR gene transfer. J Immunol. 1995 Feb 1;154(3):998-1006. Click here to download.

  11. Beckman EM, Porcelli SA, Morita CT, Behar SM, Furlong ST, Brenner MB. Recognition of a lipid antigen by CD1-restricted ab+ T cells. Nature. 1994 Dec 15;372(6507):691-4. Click here to download.

  12. Bukowski JF, Morita CT, Brenner MB. Recognition and destruction of virus-infected cells by human γδ CTL. J Immunol. 1994 Dec 1;153(11):5133-40. Click here to download.

  13. Morita CT, Parker CM, Brenner MB, Band H. TCR usage and functional capabilities of human γδ T cells at birth. J Immunol. 1994 Nov 1;153(9):3979-88. Click here to download.

  14. Tanaka Y, Sano S, Nieves E, De Libero G, Rosa D, Modlin RL, Brenner MB, Bloom BR, Morita CT. Nonpeptide ligands for human γδ T cells. Proc Natl Acad Sci U S A. 1994 Aug 16;91(17):8175-9. Click here to download.

  15. Porcelli S, Morita CT, Brenner MB. CD1b restricts the response of human CD4-8- T lymphocytes to a microbial antigen. Nature. 1992 Dec 10;360(6404):593-7.

  16. Morita CT, Verma S, Aparicio P, Martinez C, Spits H, Brenner MB. Functionally distinct subsets of human γδ T cells. Eur J Immunol. 1991 Dec;21(12):2999-3007.

  17. Panchamoorthy G, McLean J, Modlin RL, Morita CT, Ishikawa S, Brenner MB, Band H. A predominance of the T cell receptor Vg2Vd2 subset in human mycobacteria-responsive T cells suggests germline gene encoded recognition. J Immunol. 1991 Nov 15;147(10):3360-9. Click here to download.

  18. Uyemura K, Deans RJ, Band H, Ohmen J, Panchamoorthy G, Morita CT, Rea TH, Modlin RL. Evidence for clonal selection of γδ T cells in response to a human pathogen. J Exp Med. 1991 Sep 1;174(3):683-92. Click here to download.

Pre-1990

  1. Morita CT, Godfrey WL, Goodman JW, Lewis GK. Arsonate-specific murine T cell clones. III. Correlation between clonotype expression and fine specificity for analogs of L-tyrosine-p-azobenzenearsonate. J Immunol. 1986 Oct 1;137(7):2139-44. Click here to download.

  2. Morita CT, Goodman JW, Lewis GK. Arsonate-specific murine T cell clones. II. Delayed-type hypersensitivity induced by P-azobenzenearsonate-L-tyrosine (ABA-Tyr). J Immunol. 1985 May;134(5):2894-9. Click here to download.

  3. Char DH, Wood IS, Huhta K, Rand N, Morita CT, Howes EL Jr. Retinoblastoma: tissue culture lines and monoclonal antibody studies. Invest Ophthalmol Vis Sci. 1984 Jan;25(1):30-40.

  4. Char DH, Rand N, Howes EL Jr, Lyon H, Morita CT. Antiretinoblastoma monoclonal antibodies. Retina. 1983;3(3):200-5.

  5. Siebert AE Jr, Blitz RR, Morita CT, Good AH. Taenia crassiceps: serum and surface immunoglobulins in metacestode infections of mice. Exp Parasitol. 1981 Jun;51(3):418-30.

Reviews

  1. Morita CT, Mariuzza RA, Brenner MB. Antigen recognition by human γδ T cells: pattern recognition by the adaptive immune system. Springer Semin Immunopathol. 2000;22(3):191-217. Click here to download.

  2. Morita CT, Lee HK, Leslie DS, Tanaka Y, Bukowski JF, Marker-Hermann E. Recognition of nonpeptide prenyl pyrophosphate antigens by human γδ T cells. Microbes Infect. 1999 Mar;1(3):175-86. Click here to download.

  3. Chu DH, Morita CT, Weiss A. The Syk family of protein tyrosine kinases in T-cell activation and development. Immunol Rev. 1998 Oct;165:167-80.

  4. Porcelli SA, Morita CT, Modlin RL. T-cell recognition of non-peptide antigens. Curr Opin Immunol. 1996 Aug;8(4):510-6. Review. Click here to download.

  5. Morita CT, Tanaka Y, Bloom BR, Brenner MB. Direct presentation of non-peptide prenyl pyrophosphate antigens to human γδ T cells. Res Immunol. 1996 Jun;147(5):347-53. Review. Click here to download.

  6. Tanaka Y, Brenner MB, Bloom BR, Morita CT. Recognition of nonpeptide antigens by T cells. J Mol Med. 1996 May;74(5):223-31.

  7. Band H, Porcelli SA, Panchamoorthy G, McLean J, Morita CT, Ishikawa S, Modlin RL, Brenner MB. Antigens and antigen-presenting molecules for γδ T cells. Curr Top Microbiol Immunol. 1991;173:229-34.

  8. Band H, Panchamoorthy G, Mclean J, Morita CT, Ishikawa S, Modlin R, Brenner MB. Recognition of mycobacterial antigens by γδ T cells. Res Immunol. 1990 Sep;141(7):645-51. Review.

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