Aspergillus Antibodies by Complement Fixation and Immunodiffusion

Label Mnemonic:	ASPERG
Epic code:	LAB2634
Downtime form:	A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Serum

Collection Medium:

Red top tube 5 mL (Clot Activator)

Minimum:

Preferred Minimum: 0.5 mL serum
Absolute Minimum: 0.2 mL serum

Rejection Criteria:

Body fluid.

Turn Around Time:

3-6 days upon receipt at reference laboratory

Reference Range:

None detected

Interpretive Data:

In general, immunodiffusion measures IgG and a positive result may suggest past infection. The test is positive in about 90% of sera from patients with aspergilloma and 50-70% of patients with allergic bronchopulmonary aspergillosis. A negative test (none detected) does not exclude aspergillosis.

Comments:

This test uses culture filtrates of Aspergillus fumigatus, Aspergillus flavus, Aspergillus niger, and Aspergillus terreus.

Methodology:

Semi-Quantitative Complement Fixation/Immunodiffusion

CPT Code:

86606