Salivary Gland Tumor Fusion Panel with Interpretation
Label Mnemonic: | SGTF |
Epic code: | LAB8690 |
Order form: | Molecular Oncology Requisition |
Supply order: | Supply Order Form |
Billing: | Billing Policies |
CPT code: | 81445 |
Specimen(s):
Formalin-fixed, paraffin embedded tissue block, or 10 unstained 4
micron-thick section on non-plus slides and one H&E stained
section or Fine needle aspirate
Rejection Criteria:
Specimens that have been decalcified will not be accepted.
Testing Schedule:
Weekly
Turn Around Time:
21 days
Reference Range:
Fusion or mutation not detected.
Interpretive Data:
Detected
Not detected
Not detected
Comments:
Tissue sections are reviewed by a pathologist. RNA is isolated from
the selected area of the sample. Anchored multiplex PCR for a
targeted next-generation sequencing is performed. The sequenced
sample is a reverse transcription PCR-amplified fragenbt library in
which each sample is uniquely identified by ligation of a short
oligonucleotide barcode. The resultant sequence identifies the exons
of the fusion transcript arising from the specific gene target and
the partnet gene.
The panel target gene rearrangements of these gene targets: ETV6, EWSR1, HMGA2, HRAS, MAML2, MYB, MYBL1, NFIB, NTRK3, NUTM1, PLAG1, PRKD1, PRKD2, PRKD3.
Read more....
The panel target gene rearrangements of these gene targets: ETV6, EWSR1, HMGA2, HRAS, MAML2, MYB, MYBL1, NFIB, NTRK3, NUTM1, PLAG1, PRKD1, PRKD2, PRKD3.
Read more....
Methodology:
Massively paraellel Next Generation RNA sequencing by synthesis,
semiconductor technology, Illumia
Sample Storage:
Room Temperature.
Transport Instructions:
Place specimen into zip-lock type bag, seal bag.
Place requisition into outside pocket of bag.
Recommend early AM overnight shipping or equivalent if not on courier service.
Protect block or slides from excessive heat and ship in cooled container during summer months.
Place requisition into outside pocket of bag.
Recommend early AM overnight shipping or equivalent if not on courier service.
Protect block or slides from excessive heat and ship in cooled container during summer months.
CPT Code:
81445