Alcohols Panel (Methanol, Ethanol, Isopropanol, Acetone)
Label Mnemonic: ALCH
Epic Lab Code: LAB551
Downtime Form: A-1a Miscellaneous Request
Chemistry
6240 RCP
356-3527
Specimen(s):
Plasma
Collection Medium:
Plasma Separator Tube 4.5 mL
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
3 mL whole blood in light green top tube or TWO Microtainer® devices
Rejection Criteria:
Medico-legal specimens are not accepted.
Testing Schedule:
0700-1530 Monday through Friday. For additional services, contact Clinical Pathology Resident on-call at pager #3404.
Turn Around Time:
4 hours (upon receipt in laboratory)
Reference Range:
Ethanol intoxication begins in the 50-100 mg/dL range.

Clinical toxicity for methanol and isopropanol can occur at concentrations of 10 mg/dL or greater.

Critical Values:
  Methanol 10 mg/dL or greater
  Isopropanol 10 mg/dL or greater
  Ethanol 300 mg/dL or greater
Comments:
May be ordered after ethanol/volatiles screen (EVS) with an unexplained osmolar gap >15. This procedure individually quantitates methanol, ethanol, isopropanol and acetone.

Availability: As needed. Profile result codes: methanol, ethanol, acetone, isopropanol.

This test requires approval of Clinical Pathology Resident on-call (pager #3404). May be ordered after ethanol/volatiles screen (EVS) with an unexplained osmolar gap >15. This procedure individually quantitates methanol, ethanol, isopropanol and acetone. Availability: As needed. Profile result codes: methanol, ethanol, acetone, isopropanol.
Test Limitations:
Sample Integrity Confirmation References: (1) Brent J et al. Fomepizole for the treatment of methanol poisoning. New Engl J Med 344: 424-429, 2001. (2) Lynd LD et al. An evaluation of the osmole gap as a screening test for toxic alcohol poisoning. BMC Emerg Med 8: 5, 2008. (3) Krasowski MD et al. A retrospective analysis of glycol and toxic alcohol ingestion: utility of anion and osmolal gaps. BMC Clin Pathol 12: 1, 2012.
Methodology:
Gas Chromatography
CPT Code:
80320