Pemphigus Antibody Panel - Epithelial Cell Surface Antibodies and Desmoglein 1 and 3
| Label Mnemonic: | PEMPHI PAN |
| Epic code: | LAB8711 |
| Downtime form: | Doctor/Provider Orders - Pathology Core and Specialty Care Nursery |
Commercial Mailout Laboratory
6240-8 RCP
356-8593
6240-8 RCP
356-8593
Specimen(s):
Serum
Collection Medium:
 |
| Red top tube 5 mL (Clot Activator) |
Minimum:
Preferred Minimum: 2 mL serum
Absolute Minimum: 0.5 mL serum
Absolute Minimum: 0.5 mL serum
Rejection Criteria:
Hemolyzed or lipemic specimens.
Turn Around
Time:
4-9 days upon receipt at reference laboratory
Reference Range:
By report
Comments:
This is the preferred panel for initial assessment and disease
monitoring in IgG-variant pemphigus. Pemphigus vulgaris and pemphigus
foliaceus are the most common types of pemphigus with blistering and
erosive disease affecting skin and mucous membranes.
Panel components include antibody testing for IgG epithelial cell surface and IgG desmoglein 1 and 3.
To screen for pemphigus along with other possible immunobullous diseases, order concurrently with Pemphigoid Antibody Panel - Epithelial Basement Membrane Zone Antibodies, IgG and IgA, BP180 and BP230.
Panel components include antibody testing for IgG epithelial cell surface and IgG desmoglein 1 and 3.
To screen for pemphigus along with other possible immunobullous diseases, order concurrently with Pemphigoid Antibody Panel - Epithelial Basement Membrane Zone Antibodies, IgG and IgA, BP180 and BP230.
Methodology:
Semi-Quantitative Complement Fixation/Indirect Immunofluorescence (IIF)/Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)
CPT Code:
88346, 88350, 83516 x2