First Trimester Screen Only - Iowa Maternal Screening

Label Mnemonic:	FTRIIMS
Epic code:	LAB8342
Downtime form:	Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Serum

Specimen Instructions:

Collect during first trimester when the ultrasound crown rump 
length (CRL) is 32-80 mm at 10 weeks-13 weeks 6 days.  Nuchal 
translucency (NT) measurement is REQUIRED and must be performed when 
the CRL is 32-80 mm.

Patient weight (kg), ultrasound date, CRL (mm) and NT measurement (mm) 
at time of ultrasound and sonographer name required.  If IVF pregnancy, 
the age of the egg donor is required.

Refrigerate specimen if not transported within 24 hours of collection 
to reference laboratory.

Collection Medium:

Red top tube 5 mL (Clot Activator)

Minimum:

3 mL whole blood in Red Top Tube or 1 mL serum

Rejection Criteria:

Plasma or specimen older than 9 days. Sample not collected within the required gestational age range.

Delivery Instructions:

Deliver to laboratory after collection.

Turn Around Time:

3-5 days upon receipt at reference laboratory

Reference Range:

By report - PAPP-A, hCG, and NT measurement calculated Multiples of the Median (MoMs) based on gestational age.

Comments:

First trimester screening test for DS and T18. Testing does not include AFP for open NTD screening.

This test cannot be performed on multiples.

If this test is performed, recommended that a NTD Screen - Iowa Maternal Screening (LAB8341) be performed in the second trimester.

Methodology:

Quantitative Chemiluminescent Immunoassay

CPT Code:

84702, 84163

See also:
NTD Screen - Iowa Maternal Screening, Serum