Paraneoplastic Autoantibodies
Label Mnemonic: NEOPLAS
Epic Lab Code: LAB7735
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Serum
Collection Medium:
Red top tube 5 mL (Clot Activator)
Minimum:
2 mL serum in red top tube
Rejection Criteria:
Contaminated, heat-inactivated, hemolyzed, or lipemic specimens.
Turn Around Time:
1-9 days upon receipt at reference laboratory
Reference Range:
Components Reference Interval Purkinje Cell/Nuclear IgG Scm None Detected Neuronal Nuclear Antibody (ANNA) < 1:10 IFA Titer, IgG Purkinje Cell Antibody, Titer < 1:10 Neuronal Nuclear Antibodies (Hu, Ri, Yo) None Detected IgG by Immunoblot Note: Purkinje Cell (PCCA) antibody and Neuronal Nuclear (ANNA) antibody IgG are screened by IFA. If the IFA screen is indeterminate, then a Neuronal Nuclear Antibodies (Hu, Ri, and Yo) IgG by Immunoblot will be added. If the IFA screen is positive at 1:10 or greater, then a PCCA/ANNA antibodies titer and Neuronal Nuclear Antibodies (Hu, Ri, and Yo) IgG by Immunoblot will be added. Additional charges apply.
Comments:
PCCA/ANNA antibodies are screened by IFA. If the IFA screen is positive at 1:10, then a specific titer (PCCA or ANNA) and immunoblot will be added. Additional charges apply.
Methodology:
Semi-Quantitative Indirect Fluorescent Antibody/Qualitative Immunoblot
CPT Code:
86255; if reflexed add 83516 and/or 86256