Varicella-Zoster Virus PCR, Other Fluids
Label Mnemonic: VZVPR
Epic Lab Code: LAB7466
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Amniotic, Vitreous, Ocular or Aqueous Fluid
Collection Medium:
Sterile container
Minimum:
Preferred Minimum: 1.0 mL fluid
Absolute Minimum: 0.3 mL fluid

Collect in sterile container: Submit 0.5 mL amniotic fluid. If submitting one of the following vitreous/ocular/or aqueous fluid, collect 0.5 mL if ordering one laboratory test. If multiple tests ordered, collect 1.0 mL of this fluid.
(This amount of sample will perform from 1 up to 4 viral tests).
Delivery Instructions:
Submit specimen to laboratory as soon as possible after collection period is completed.
Turn Around Time:
24 hours upon receipt at reference laboratory
Reference Range:
Negative
Interpretive Data:
Detection of varicella-zoster virus (VZV) DNA in clinical specimens supports the clinical diagnosis of infection due to this virus.

This LightCycler PCR assay does not yield positive results with other herpesvirus gene targets (herpes simplex virus, cytomegalovirus, Epstein-Barr virus).
Comments:
Useful for rapid (qualitative) detection of varicella-zoster virus DNA in clinical specimens for laboratory diagnosis of disease due to this virus.

Cautions: A negative result does not exclude the possibility of varicella-zoster virus (VZV) infection.

The reference range is typically "negative" for this assay. This assay is only to be used for patients with a clinical history and symptoms consistent with VZV infection, and must be interpreted in the context of the clinical picture. This test is not used to screen asymptomatic patients.
Methodology:
Real-Time Polymerase Chain Reaction (PCR)/DNA Probe Hybridization
CPT Code:
87798
 
See also:
Cytomegalovirus by PCR, Other Fluids, Vitreous, Ocular or Aqueous Fluid
Herpes Simplex Virus PCR, Other Fluids, Amniotic, Vitreous, Ocular or Aqueous Fluid
Toxoplasma gondii PCR, Other Fluids, Amniotic, Vitreous, Ocular or Aqueous Fluid