C3 Nephritic Factor Analysis
Label Mnemonic: C3NEF
Epic code: LAB2765
Downtime form: A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Commercial Mailout Laboratory
6240-8 RCP
356-8593
Specimen(s):
Serum
Collection Medium:
Red top tube 5 mL (Clot Activator)
Minimum:
Preferred Minimum: 1 mL serum
Absolute Minimum: 0.25 mL serum
Rejection Criteria:
No gel tubes
Delivery Instructions:
Allow blood to clot at room temp or 37°C for 20 to 60 minutes. Centrifuge to thoroughly remove cells and immediately transfer cell- free serum to a fresh tube and freeze the cell-free serum on dry ice or at -70°C.
Turn Around Time:
14 days upon receipt at reference laboratory
Reference Range:
Normal: 0 - 0.26
Equivocal: 0.27 - 0.33
Positive: > 0.34
Interpretive Data:
The value is the ratio of C3 fragments to intact C3. If a C3 nephritic factor is present, it will stabilize the C3 converting enzyme, resulting in more C3 being cleaved and the measured ratio will be higher.
Methodology:
Immunofixation Electrophoresis
CPT Code:
86161
 
See Additional Information:
Specimens Requiring Immediate Delivery