Neuromyelitis Optica/Aquaporin-4-IgG
Label Mnemonic: NMOIGGCSF
Epic Lab Code: LAB8503
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
CSF
Collection Medium:
CSF collection kit
Minimum:
Preferred Minimum: 1 mL of spinal fluid
Absolute Minimum: 0.5 mL of spinal fluid
Delivery Instructions:
Deliver to laboratory immediately after collection.
Testing Schedule:
Include relevant clinical information, name, phone number, mailing address, and e-mail address (if applicable) of ordering physician.
Turn Around Time:
4 days upon receipt in reference laboratory
Reference Range:
Negative
Comments:
Useful for:
*Diagnosis of a neuromyelitis optica spectrum disorder (NMOSD)
*Diagnosis of autoimmune AQP4 channelopathy
*Distinguishing NMOSD from multiple sclerosis early in the course
 of disease

ALGORITHM: When the results of this assay require further evaluation, the titer assay will be performed at an additional charge.
Methodology:
Fluorescence-Activated Cell Sorting Assay (FACS)
CPT Code:
86255
86256-NMO/AQP4-IgG FACS titer (if appropriate)
 
See Additional Information:
Specimens Requiring Immediate Delivery