Angiotensin Converting Enzyme (ACE) for Gaucher Clinical Drug Monitoring

Label Mnemonic:	GENACE
Epic code:	LAB2593
Downtime form:	Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Serum

Collection Medium:

Red top tube 5 mL (Clot Activator)

Minimum:

Adult Minimum: 2.0 mL serum
Pediatric Minimum: 1.0 mL serum

Rejection Criteria:

Specimens not received at reference laboratory within 4 days of specimen collection; do not collect on Fridays, holidays, day before a holiday, or weekends. Hemolyzed Specimens.

Turn Around Time:

7-14 days

Reference Range:

By report

Comments:

The Angiotensin converting enzyme assay uses tripeptide 
(hippuryl-his-leu) as subtrate and o-phthaldialdehyde for fluroescent 
derivatization.

Testing used for patients on Cerezyme (part of Gaucher Disease clinical 
drug monitoring including ACE, TRAP and CHITO).

Methodology:

Fluorometric Enzyme assay

CPT Code:

82164