Chitotriosidase (CHITO) for Gaucher clinical drug monitoring
Commercial Mail-out Laboratory
|Red top tube 5 mL (Clot Activator)
Preferred Pediatric Minimum: 2.0 mL serum
Absolute Pediatric Minimum: 1.0 mL serum
Specimens must be received at reference laboratory within 4 days of
specimen collection; do not collect on Fridays, holidays, day before a
holiday, or weekends.
1-2 weeks upon receipt at reference laboratory
4 - 120 nmoles/hr/mL: median=22 nmoles/hr/mL
The Chitotriosidase fluorometric enzyme assay uses
4-methylumbelliferyl-beta-D-triacetylchitotrioside as substrate.
Testing used for patients on Cerezyme (part of Gaucher Disease
drug monitoring including ACE, TRAP and CHITO).
Fluorometric enzyme assay