Chitotriosidase (CHITO) for Gaucher clinical drug monitoring
Label Mnemonic: GENCHITO
Epic Lab Code: LAB2845
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Serum
Collection Medium:
Red top tube 5 mL (Clot Activator)
Minimum:
Preferred Pediatric Minimum: 2.0 mL serum
Absolute Pediatric Minimum: 1.0 mL serum
Rejection Criteria:
Specimens must be received at reference laboratory within 4 days of specimen collection; do not collect on Fridays, holidays, day before a holiday, or weekends.
Turn Around Time:
1-2 weeks upon receipt at reference laboratory
Reference Range:
4 - 120 nmoles/hr/mL: median=22 nmoles/hr/mL
Comments:
The Chitotriosidase fluorometric enzyme assay uses 4-methylumbelliferyl-beta-D-triacetylchitotrioside as substrate.

Testing used for patients on Cerezyme (part of Gaucher Disease clinical drug monitoring including ACE, TRAP and CHITO).
Methodology:
Fluorometric enzyme assay
CPT Code:
82657