|Downtime form:||A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery|
|Green top tube 4 mL (Na Heparin)|
Absolute Minimum: 0.1 mL
1. Centrifuge and aliquot plasma into plastic vial.
2. Send plasma frozen.
< or =2.0 mg/L
< or = 0.3 mg/L
Mild elevations of these cholesterol precursors can be detected in patients with hypercholesterolemia and patients treated with some antipsychotic or antidepressant medications including haloperidol, aripiprazole, and trazodone. However, the 7-DHC to cholesterol ratio is typically elevated only in SLO patients.
On very rare occasions, 7-dehydrocholesterol is not elevated in patients with Smith-Lemli-Opitz syndrome.
Cholesterol screening tests are unreliable for diagnosis for Smith-Lemli-Opitz syndrome.
Some antipsychotic or antidepressant medications such as aripiprazole and trazodone cause false elevations in 7-dehydrocholesterol.
Specimens Requiring Immediate Delivery