Rheumatoid Factor

Label Mnemonic:	RF
Epic code:	LAB206
Downtime form:	A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Chemistry
6240 RCP
356-3527

Specimen(s):

Plasma

Collection Medium:

Plasma Separator Tube 4.5 mL

Alternate Collection Media:

Call laboratory for additional acceptable specimen collection containers.

Minimum:

3 mL; whole blood in light green top tube or ONE Microtainer^®.

Testing Schedule:

24 hrs/day, 7 days a week, including holidays.

Turn Around Time:

1 hour (upon receipt in laboratory)

Reference Range:

<14 IU/mL

Test Limitations:

Criterion: Recovery within plus or minus 10% of initial value.

Icterus: No significant interference up to an I index of 60.

Hemolysis: No significant interference up to an H index of 300 
(approximate hemoglobin concentration: 300 mg/dL).

Lipemia (Intralipid): No significant interference up to an L index of 
2000.

There is poor correlation between turbidity and triglycerides 
concentration.

No high-dose hook effect up to RF activities of 6000 IU/mL.

Drugs: No interference was found at therapeutic concentrations using 
common drug panels.

Reference:
Glick MR, Ryder KW, Jackson SA. Graphical Comparisons of Interferences 
in Clinical Chemistry Instrumentation. Clin Chem 1986;32:470-474.

Methodology:

Immunoturbidimetric Assay

CPT Code:

86431