Entamoeba Histolytica Antibody, IgG
Commercial Mail-out Laboratory
Parallel testing is preferred and
convalescent specimens must be received within 30 days from receipt of
the acute specimens. Mark specimens plainly as acute or
|Red top tube 5 mL (Clot Activator)
Preferred Minimum: 1 mL serum
Absolute Minimum: 0.1 mL serum
Contaminated, heat-inactivated, hemolyzed, or severely lipemic
Deliver to laboratory immediately after collection.
1-5 days upon receipt at reference laboratory.
8 U or less: Negative - No significant level of detectable
E. histolytica IgG antibody.
9-11 U: Equivocal - Repeat testing in 10-14 days may be helpful.
12 U or greater: Positive - IgG antibody to E. histolytica
detected, suggestive of a current or past infection.
Seroconversion between acute and convalescent sera is considered
strong evidence of recent infection. The best evidence for infection
is a significant change on two appropriately timed specimens where
both tests are done in the same laboratory at the same time.
Note: In the case of extraintestinal complications, a positive
antibody can indicate amebiasis even though stool findings are
Semi-Quantitative Enzyme-Linked Immunosorbent Assay