Immunoglobulin M (IgM), Individual Quant

Label Mnemonic:	IGM
Epic code:	LAB72
Downtime form:	Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Chemistry
6240 RCP
356-3527

Specimen(s):

Plasma

Collection Medium:

Plasma Separator Tube 4.5 mL

Alternate Collection Media:

Call laboratory for additional acceptable specimen collection containers.

Minimum:

3 mL whole blood from light green top tube or ONE Microtainer^®.

Rejection Criteria:

Specimens received in Sodium Citrate tubes

Testing Schedule:

24 hrs/day, 7 days a week, including holidays.

Turn Around Time:

1 hour (upon receipt in laboratory)

Reference Range:

 0 - 1 yrs       0 - 145 mg/dL
 1 - 3 yrs      19 - 146 mg/dL
 4 - 6 yrs      24 - 210 mg/dL
 7 - 9 yrs      31 - 208 mg/dL
1O - 11 yrs     31 - 179 mg/dL
12 - 13 yrs     35 - 239 mg/dL
14 - 15 yrs     15 - 188 mg/dL
16 - 19 yrs     23 - 259 mg/dL
≥ 19 yrs        40 - 230 mg/dL

Test Limitations:

Criterion: Recovery within plus or minus 10% of initial values.

Icterus: No significant interference up to an I index of 60 
(approximate conjugated and unconjugated bilirubin concentration: 60 
mg/dL).

Hemolysis: No significant interference up to an H index of 1000. 
(approximate hemoglobin concentration: 1000 mg/dL)

Lipemia (Intralipid): No significant interference up to an L index of 
2000.  There is poor correlation between turbidity and triglycerides 
concentration.

There is no cross-reaction between IgM and IgA or IgG under assay 
conditions.

Sera with ill-defined characteristics should be subject to protein 
electrophoresis to identify a possible antigen excess (e.g. 
gammopathy).

A high dose hook effect may occur at IgM concentrations of greater 
than 3,000 mg/dL (30 g/L).

Methodology:

Immunoturbidimetric

CPT Code:

82784