Immunoglobulin M (IgM), Individual Quant
Label Mnemonic: | IGM |
Epic Lab Code: | LAB72 |
Downtime Form: | A-1a General Laboratory Requisition |
Chemistry
6240 RCP
356-3527
6240 RCP
356-3527
Specimen(s):
Plasma
Collection Medium:
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Plasma Separator Tube 4.5 mL |
Alternate
Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
3 mL whole blood from light green top tube or ONE
Microtainer®.
Rejection Criteria:
Specimens received in Sodium Citrate tubes
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around
Time:
1 hour (upon receipt in laboratory)
Reference Range:
0 - 1 yrs 0 - 145 mg/dL
1 - 3 yrs 19 - 146 mg/dL
4 - 6 yrs 24 - 210 mg/dL
7 - 9 yrs 31 - 208 mg/dL
1O - 11 yrs 31 - 179 mg/dL
12 - 13 yrs 35 - 239 mg/dL
14 - 15 yrs 15 - 188 mg/dL
16 - 19 yrs 23 - 259 mg/dL
> 19 yrs 40 - 230 mg/dL
Test
Limitations:
Criterion: Recovery within plus or minus 10% of initial values.
Icterus: No significant interference up to an I index of 60
(approximate conjugated and unconjugated bilirubin concentration: 60
mg/dL).
Hemolysis: No significant interference up to an H index of 1000.
(approximate hemoglobin concentration: 1000 mg/dL)
Lipemia (Intralipid): No significant interference up to an L index of
2000. There is poor correlation between turbidity and triglycerides
concentration.
There is no cross-reaction between IgM and IgA or IgG under assay
conditions.
Sera with ill-defined characteristics should be subject to protein
electrophoresis to identify a possible antigen excess (e.g.
gammopathy).
A high dose hook effect may occur at IgM concentrations of greater
than 3,000 mg/dL (30 g/L).
Methodology:
Immunoturbidimetric
CPT Code:
82784