The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK


Folate (RBC)
Order Code: EFOL
Order Form: A-1a Miscellaneous Request or IPR Req
  Commercial "Mail-out" Laboratory
6240 RCP
356-3527
Specimen
Whole Blood
Collection Medium:
Lavender top tube (EDTA)
Minimum:
Adult minimum: 1 ml whole blood
Pediatric minimum: 0.2 ml whole blood
Delivery Instructions:
Deliver to laboratory immediately after collection.
Analytic Time:
4 days
Reference Range:
280 - 903 ng/mL
Comments:
Hematocrit automatically included at no additional charge. To add 
folate to specimen already submitted for CBC, call lab within 1 hour of 
specimen collection.

Low folate intake, malabsorption, pregnancy, and drugs such as 
phenytoin are causes of folate deficiency. Folate deficiency is also 
associated with chronic alcoholism. Both folate and vitamin B12 
deficiency cause macrocytic anemia. Appropriate treatment depends on 
the differential diagnosis of the deficiency. Serum folate measurement 
provides an index of folate status. However, because folate is much 
more concentrated in RBCs than in serum, RBC folate measurement more 
closely reflects tissue stores and is considered the most reliable 
indicator of folate status.
Methodology:
Chemiluminescent Immunoassay
CPT Code:
82747
 
See also:
Folate, Serum
 
See Additional Information:
Specimens Requiring Immediate Delivery

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Updated: 05/16/2007

Note: The information contained in this handbook is for use by personnel of University of Iowa Health Care. No other use is implied or intended.