The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK


Catecholamines, Fractionated
Order Code: CATNBSU
Order Form: A-1a General Lab or IPR Req
  Commercial "Mail-out" Laboratory
6240 RCP
356-3527
Specimen
Urine More information
Collection Medium:
Urine - 24 hour/timed urine glass container with acid
Minimum:
24 hr collection; with 25 ml 6N HCl as preservative (preferred) or 
random urine.  For peds, contact Pharmacy for correct amount of 
concentrated HCl.
Analytic Time:
1 week
Reference Range:
                   Range        Mean          Range           Mean
                   (ug/g        (ug/g     (ug/24 hours)   (ug/24 hours)
                creatinine)  creatinine)
Norepinephrine
  Infants:
  < 1 Year:       37 - 195       105     Not determined Not determined

  Children:
  1-10 years:     24 - 140        50     Not determined Not determined

  Older children
  and adults:     12 - 110        36       16 - 125           45

Epinephrine
  Infants:
  < 1 Year:        2 - 180       116     Not determined Not determined

  Children:
  1-10 years:     20 - 149        80     Not determined Not determined

  Older children
  and adults:      9 -  25        19         3 - 38           16

Pediatric values were determined on both random and 8 hour urine 
collections.
Comments:
VMA, Catecholamines and Metanephrines may be done on same collection.  
Alpha methylodopa (Aldomet) and Labetalol (Normodyne) will falsely 
elevate the apparent concentration of urine catecholamines. Collection 
containers available from pharmacy.

Includes: Epidenphrine and Norepinephrine

If screening for Neuroblastoma, the following tests need to be ordered: 
CATNBSU (Catecholamines, Fractionated), DOPNBSU (Dopamine), HVANBSU 
(Homovanillic Acid), METNBSU (Metanephrines), VMANBSU (Vanillylmandelic 
Acid).
Methodology:
HPLC electrochemical detector, colormetric
CPT Code:
82384 Fractionated Catecholamines; 82570 Creatinine, Urine
 
See also:
Dopamine, Urine
Homovanillic Acid (HVA), Urine
Metanephrines, Urine
Neuroblastoma Screen, Urine
Vanillylmandelic Acid (VMA), Urine
 
See Additional Information:
Urine Tests Requiring Preservatives, Refrigeration or Special Containers

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Updated: 06/05/2007

Note: The information contained in this handbook is for use by personnel of University of Iowa Health Care. No other use is implied or intended.