Neurokinin A (Substance K)
| Order Code: | NEUROA |
| Epic Lab Code: | LAB3698 |
| Order Form: | A-1a Miscellaneous Request or Epic Req |
Commercial Mail-out Laboratory
6240 RCP
356-3527
6240 RCP
356-3527
Specimen:
Plasma
Minimum:
1 mL plasma from a Special Z-GI preservative collection tube obtained from reference laboratory. Mailouts has these tubes, call 356-8593.
Delivery Instructions:
Submit specimen to laboratory as soon as possible after collection.Specimen
Instructions:
Patient should not be on any medications that affect hypertension,
gastrointestinal functions, or pain relievers, if possible, for at
least 48 hours prior to collection of specimen.
For tumor/tissue and various fluids (i.e. CSF, peritoneal, synovial,
etc.) contact Commerical Mailouts (356-8593) for requirements and
special handling.
Testing Schedule:
Varies
Analytic Time:
2 weeks upon receipt at reference laboratory
Reference Range:
Up to 40 pg/ml
Comments:
Contact Commercial Mailouts at 356-8593 to obtain collection tubes for
this testing. No other specimen collection container is acceptable by
the reference laboratory.
Patients should be fasting for 10-12 hours prior to specimen
collection. Antacid medications or medications that affect intestinal
motility should be discontinued, if possible, for at least 48 hours
prior to collection.
Neurokinin A is a ten amino acid putative transmitter synthesized in
the neurons it is present in. Neurokinin A is a member of the family
called Tachykinins which also include Neurokinin B, Substance P,
Physalaemin, and Eledoisin. Neurokinin A shares 6 of 10 peptide
homologies with Neurokinin B even though they are produced by different
genes. Neurokinin A is also very similar in structure to Substance P
and produces some of the same biological actions as Substance P.
Neurokinin A is a potent bronchoconstrictor. In the gut, Neurokinin A
is produced by the intrinsic enteric nervous system.
Methodology:
Direct Radioimmunoassay
CPT Code:
83519
