Angiotensin Converting Enzyme (ACE) for Gaucher Clinical Drug Monitoring, Serum

The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK

Angiotensin Converting Enzyme (ACE) for Gaucher Clinical Drug Monitoring
Order Code: GENACE Epic Lab Code: LAB2593 Order Form: A-1a Miscellaneous Request or Epic Req		Commercial "Mail-out" Laboratory 6240 RCP 356-3527

Specimen:

Serum

Collection Medium:

Red top tube

Minimum:

Adult minimum:  2.0 mL serum
Pediatric minimum:  1.0 mL serum

Rejection Criteria:

Specimens not received at reference laboratory within 4 days of 
specimen collection; do not collect on Fridays, holidays, day before a 
holiday, or weekends.  Hemolyzed Specimens.

Analytic Time:

7-14 days

Reference Range:

By report

Comments:

The Angiotensin converting enzyme assay uses tripeptide 
(hippuryl-his-leu) as subtrate and o-phthaldialdehyde for fluroescent 
derivatization.

Testing used for patients on Cerezyme (part of Gaucher Disease clinical 
drug monitoring including ACE, TRAP and CHITO).

Methodology:

Fluorometric Enzyme assay

CPT Code:

See also:
Chitotriosidase (CHITO) for Gaucher clinical drug monitoring, Serum
Tartrate Resistant Acid Phosphatase (TRAP) for Gaucher clinical drug monitoring, Serum

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Updated: 02/25/2009

Note: The information contained in this handbook is for use by personnel of University of Iowa Health Care. No other use is implied or intended.