Chitotriosidase (CHITO) for Gaucher clinical drug monitoring, Serum

Chitotriosidase (CHITO) for Gaucher clinical drug monitoring

Order Code:	GENCHITO
Epic Lab Code:	LAB2845
Order Form:	A-1a Miscellaneous Request or Epic Req

Commercial Mail-out Laboratory
6240 RCP
356-3527

Specimen:

Serum

Collection Medium:

Red top tube

Minimum:

Preferred Pediatric minimum: 2.0 mL serum Absolute Pediatric minimum: 1.0 mL serum

Rejection Criteria:

Specimens must be received at reference laboratory within 4 days of specimen collection; do not collect on Fridays, holidays, day before a holiday, or weekends.

Analytic Time:

1 week upon receipt at reference laboratory

Reference Range:

4 - 120 nmoles/hr/mL: median=22 nmoles/hr/mL

Comments:

The Chitotriosidase fluorometric enzyme assay uses 4-methylumbelliferyl-beta-D-triacetylchitotrioside as substrate. Testing used for patients on Cerezyme (part of Gaucher Disease clinical drug monitoring including ACE, TRAP and CHITO).

Methodology:

Fluorometric enzyme assay

CPT Code:

82657, 84155