Osmotic Fragility, Quantitative
Order Code: ROSF
Epic Lab Code: LAB330
Order Form: A-1a Miscellaneous Request or Epic Req
Commercial Mail-out Laboratory
6240 RCP
356-3527
Specimen:
Whole Blood
Collection Medium:
Green top tube 10 mL (Na Heparin)
Alternate Collection Media:
Light Green top tube (Lithium Heparin)
Minimum:
Preferred Minimum: 5 mL whole blood and TWO unfixed air-dried, and unstained smears Adult/Pediatric Absolute Minimum: 1 mL whole blood and TWO unfixed, air-dried, and unstained smears
Rejection Criteria:
Hemolyzed blood. Heparinized specimens greater than 48 hours old.
Delivery Instructions:
Deliver to laboratory immediately after collection.
Specimen Instructions:
Specimens should be received within 24 hours of collection; testing must be performed within 48 hours of collection. EDTA anticoagulated blood may be used if testing is performed within 24 hours of collection.
Analytic Time:
5 days upon receipt at reference laboratory
Reference Range:
Within normal curve limits. A graph will accompany laboratory report.
Interpretive Data:
For patients with acute hemolysis, a normal red cell osmotic fragility test result cannot exclude an osmotic fragility abnormality since the osmotically labile cells may be hemolyzed and not present. Recommend testing during a state of prolonged homeostasis with stable hematocrit.
Comments:
Deliver specimen to lab before 1200 (Sunday through Thursday only)-referred to reference laboratory. Pertinent clinical information should accompany the request. Analysis cannot be done on patients transfused in the preceding three months since the presence of transfused cells may render the interpretation ambiguous.
Methodology:
Spectrophotometry
CPT Code:
85555
 
See Additional Information:
Specimens Requiring Immediate Delivery