Entamoeba Histolytica Antibody, IgG

Label Mnemonic:	AMOEAB
Epic code:	LAB3067
Downtime form:	A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Serum

Specimen Instructions:

Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as acute or convalescent.

Collection Medium:

Red top tube 5 mL (Clot Activator)

Minimum:

Preferred Minimum: 1 mL serum
Absolute Minimum: 0.1 mL serum

Rejection Criteria:

Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.

Delivery Instructions:

Deliver to laboratory immediately after collection.

Turn Around Time:

1-5 days upon receipt at reference laboratory.

Reference Range:

8 U or less: Negative - No significant level of detectable 
E. histolytica IgG antibody.
9-11 U: Equivocal - Repeat testing in 10-14 days may be helpful.
12 U or greater: Positive - IgG antibody to E. histolytica 
detected, suggestive of a current or past infection.

Interpretive Data:

Seroconversion between acute and convalescent sera is considered strong evidence of recent infection. The best evidence for infection is a significant change on two appropriately timed specimens where both tests are done in the same laboratory at the same time.

Note: In the case of extraintestinal complications, a positive antibody can indicate amebiasis even though stool findings are negative.

Methodology:

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

CPT Code:

86753

See Additional Information:
Specimens Requiring Immediate Delivery