The University of Iowa (UIHC)
Department of Pathology
LABORATORY SERVICES HANDBOOK


Metanephrines, Fractionated
Order Code: METP
Order Form: A-1a Miscellaneous Request or IPR Req
  Commercial "Mail-out" Laboratory
6240 RCP
356-3527
Specimen
Plasma
Collection Medium:
Pink top tube (EDTA sprayed)
Minimum:
Adult minimum: 2.5 mL plasma from lavender top (EDTA) tube
Pediatric minimum: 1.1 mL plasma from lavender top (EDTA) tube
Analytic Time:
1 week
Reference Range:
METANEPHRINES, FRACT, PLASMA
Metanephrine
ADULT MALES:   82 pg/mL or less
ADULT FEMALES: 96 pg/mL or less

Normetanephrine
ADULT MALES:   38-175 pg/mL
ADULT FEMALES: 33-130 pg/mL

Total Metanephrines
ADULT MALES:   61-246 pg/mL
ADULT FEMALES: 50-200 pg/mL
Comments:
Patients should be relaxed in either a supine or upright position 
before blood is drawn. Patient should avoid alcohol, coffee, tea, 
tobacco and strenuous exercise prior to collection. Overnight fasting 
is preferred.
Test
Limitations:
Proper interpretation of results requires awareness of recent 
medication/drug history (e.g., antihypertensive agents, alcohol, 
cocaine) and other pre-analytical factors (e.g., stress, severe 
congestive heart failure, myocardial infarction) that influence release 
of catecholamines and metanephrines.
Methodology:
High Performance Liquid Chromatography, Electrochemical Detection
CPT Code:
83835
 
See Additional Information:
Specimens Requiring Immediate Delivery

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Updated: 04/23/2008

Note: The information contained in this handbook is for use by personnel of University of Iowa Health Care. No other use is implied or intended.