The Hund Lab

University of Iowa Carver College of Medicine

Department of Internal Medicine

3180 Med Labs
Iowa City, IA

Selected peer-reviewed publications 

  1. Lee YP, Adimoolam S, Liu M, Subbaiah PV, Glenn KA, Jonas A. Analysis of human lecithin-cholesterol acyltransferase activity by carboxyl-terminal truncation. Biochim Biophys Acta. 1997 February   18; 1344 (3): 250-261.
  2. Mattick S, Glenn KA, de Haan G, Shapiro DJ. Analysis of ligand dependence and hormone response   element synergy in transcription by estrogen receptor. J Steroid Biochem Mol Biol. 1997 March; 60 (5-6):285-294.
  3. Chusacultanachai S, Glenn KA, Rodriguez AO, Read EK, Gardner JF, Katzenellenbogen BS, Shapiro DJ. Analysis of estrogen response element binding by genetically selected steroid receptor DNA binding domain mutants exhibiting altered specificity and enhanced affinity. J Biol. Chem 1999 274 (33):23591-23598. PMID: 10438541
  4. Zhang CC, Glenn KA, Kuntz MA, Shapiro DJ. High level expression of full-length estrogen receptor in Escherichia coli is facilitated by the uncoupler of oxidative phosphorylation, CCCP. J Steroid Biochem Mol Biol. 74 (4):169-178. PMID: 11162922  
  5. Nelson RF, Glenn KA, Miller VM, Wen H, Paulson HL. A Novel route for F-box Protein-mediated      Ubiquitination Links CHIP to Glycoprotein Quality Control. J. Biol. Chem. 2006 281 (29): 20242- 20251. PMID: 16682404
  6. Nelson, R.F., Glenn, KA., Zhang, Y., Wen, H., Knutson, T., Gouvion, C., Robinson, B., Zhou, Z., Yang, B., Smith, R.J.H., Paulson, H.: Selective Cochlear Degeneration in Mice Lacking the F-box Protein, Fbx2, a Glycoprotein-Specific Ubiquitin Ligase Subunit.  J Neurosci 2007 27 (19): 5163-71. PMID: 17494702 
  7. Glenn, KA., Nelson, R., Wen, H., Mallinger, A., Paulson, H.: Novel and Diverse Substrates for a Lectin Family of Ubiquitin Ligases.  J Biol Chem 2008 283 (19): 12717-12729 PMID:PMC2442310
  8. Wen, H., Kim, N., Mallinger, A., Fuentes, E.J., Gonzalez-Alegre, P., and Glenn, K.: The F box protein FBG1 Sequesters APC2 and causes S-phase arrest. Cell Cycle. 2010 Nov 15;9(22):4506-17. PMID:21135578
  9. Gordon, K.  Glenn, K.A. and Gonzalez-Alegre, P. Exploring the influence of torsinA expression on protein quality control. Neurochem Res. 2011 Mar;36(3):452-9.PMID:21161590.
  10. Mallinger AJ, Wen, H. and Glenn, KA:  Using a ubiquitin ligase as an unfolded protein sensor. Biochem Biophys Res Commun. 2012 Feb 3;418(1):44-8.PMID:22227190.
  11. Gordon, K.  Glenn, K.A. and Gonzalez-Alegre,P. The ubiquitin ligase FBG1 promotes the degradation of the disease-linked protein torsinA through the ubiquitin proteasome pathway and macroautophagy. Neuroscience. 2012 Aug 20. PMID:22917612.  
  12. Wen, HM., Dankle, GM., and Glenn KA. : Tissue Standards Using Stain Free Gels as a Superior Approach for Aging Research. International Journal of Biochemistry and Molecular Biology, 2014, In Print.
  13. Wen, JH, Wen, HM, and Glenn, KA: FBG1 is the final arbitrator of A1AT-Z degradation. PLOS-One, 2014, Under Review.