Creatinine Clearance
Label Mnemonic: CRCL
Epic code: LAB4464
Order form: Laboratory Requisition
Supply order: Supply Order Form
Billing: Billing Policies
CPT code: 82575
Specimen(s):
Plasma & Urine
Collection Medium:
and
Plasma Separator Tube 4.5 mL Urine - 24 hour/timed plastic urine container
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
3 mL whole blood in plasma separator tube and 24 hr urine with no preservative
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
3 hours (upon receipt in laboratory)
Reference Range:
80-120 mL/min
Comments:
In Epic, this is orderable as an order panel (263313) that orders both plasma creatinine (LAB66) and a 24 hr urine creatinine. The plasma creatinine must be collected at some time during the 24 hr urine collection for the creatinine clearance to be calculated.

Not corrected for body surface area. Collection other than 24 hr will not be calculated for G/24 hr. mg/dL and clearance will be calculated on any accurately timed urine. Call lab for nomogram for body surface determination.
Methodology:
Kinetic Colorimetric
Instructions:
Draw blood during 24 hour urine collection. Record date and time of collection on requisition. Submit entire urine collection.
Sample Processing:
Submit urine in leak-proof plastic container.
Label the container with two Full patient identifiers, start date/time, and stop date/time of collection.
Centrifuge at a speed and time necessary to get barrier separation of plasma/serum and cells within 1 hour of collection. Send specimen in original tube. Do Not transfer to another tube.
Sample Storage:
Refrigerate.
Transport Instructions:
Place labeled specimen into zip-lock type biohazard bag; seal bag.
Place completed requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.
CPT Code:
82575