Carbon Dioxide (CO2 Content)
Label Mnemonic: CO2
Epic code: LAB55
Order form: Laboratory Requisition
Supply order: Supply Order Form
Billing: Billing Policies
CPT code: 82374
Specimen(s):
Plasma
Collection Medium:
Plasma Separator Tube 4.5 mL
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
3 mL whole blood from light green top tube or ONE Microtainer® for pediatric patients
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
1 hour (upon receipt in laboratory)
Reference Range:
13 years and older: 22-29 mEq/L
0-12 years old: 18-27 mEq/L
Cord blood: 15-20 mEq/L

Critical value: <10 mEq/L and >=50 mEq/L
Comments:
This test measures bicarbonate + dissolved CO2.
Test Limitations:
Plasma
Icterus: No significant interference up to an I index of 60 
(approximate conjugated and unconjugated bilirubin concentration: 60 
mg/dL).

Hemolysis: Significant negative interference at an H index greater 
than 
600.

Lipemia (Intralipid): Significant negative interference at an L index 
greater than 1800 (approximate triglycerides concentration: 3600 
mg/dL). There is poor correlation between turbidity and triglycerides 
concentration.
Methodology:
Enzymatic
Sample Processing:
Centrifuge at a speed and time necessary to get barrier separation of plasma/serum and cells within 1 hour of collection. Send specimen in original tube. Do Not transfer to another tube.
Each sample must be labeled with at least TWO full patient identifiers (First/Last Name & DOB are sufficient for non-UIHC affiliated clients) to avoid sample rejection/delays.
Sample Storage:
Refrigerate.
All sample storage requirements are intended for delivery to UIHC within 24 hours of collection for testing. If samples won't arrive in this time period, please call the UIHC Core Lab for alternative storage/shipping instructions (319-356-3527).
Transport Instructions:
Place labeled specimen into zip-lock type biohazard bag; seal bag.
Place completed requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.
CPT Code:
82374
 
See also:
Carbon Dioxide (CO2 Content)-Other, Body Fluid
 
See Additional Information:
Chemistry Critical Lab Values