Factor XIII Activity

Label Mnemonic:	F13A
Epic code:	LAB8830
Order form:	Laboratory Requisition
Supply order:	Supply Order Form
Billing:	Billing Policies
CPT code:	85290

Specimen(s):

Plasma

Collection Medium:

Light Blue top tube 2.7 mL (Na Citrate)

Minimum:

Preferred Minimum: 2 mL platelet-poor plasma
Absolute Minimum: 1 mL platelet-poor plasma

Rejection Criteria:

Serum. EDTA plasma, clotted or hemolyzed specimens.

Turn Around Time:

1-8 days upon receipt at reference laboratory

Reference Range:

Factor XIII Activity 69-143%

Comments:

First-line test to diagnose FXIII deficiency. Appropriate for evaluation of patients with a bleeding disorder presenting with normal PT, aPTT, and platelet count test results. Monitor FXIII therapy and confirm abnormalities detected on FXIII qualitative assay.

Methodology:

Chromogenic Assay

Sample Processing:

Centrifuge within two hours of draw time.
Separate plasma into plastic container and cap (glass is not acceptable).
Centrifuge a second time at 3500 RPM for 10 minutes and transfer into a new, labeled plastic tube.

Sample Storage:

Freeze specimen immediately.

Transport Instructions:

Place specimen into zip-lock type bag, seal bag.
Place requisition into outside pocket of bag.
Place dry ice on top of specimen in Styrofoam container.