MPL codon 515 Mutation
Label Mnemonic: MPLBM
Epic code: LAB8119
Order form: Comprehensive Hematopathology Requisition
Supply order: Supply Order Form
Billing: Billing Policies
CPT code: 81479
Bone Marrow Aspirate
Collection Medium:
Pink top tube 6 mL (K2-EDTA)
Adults: 3 mL bone marrow aspirate. Testing requires a dedicated collection tube.
Testing Schedule:
Turn Around Time:
7-10 days upon receipt
Reference Range:
Mutation not detected
MPL exon 10 coding sequence is amplified by polymerase chain reaction (PCR) and sequenced in both directions using next generation sequencing. The reference sequence with which this patient's DNA sequence is compared is NM_005373.1. The test will detect codon 505 and 515 mutations.
Massively parallel next generation sequencing on DNA
Sample Processing:
Label transport tube with two patient identifiers, date and time of collection.
Submit whole blood in original container. DO NOT CENTRIFUGE.
Relevant clinical information must be submitted with specimen in order to provide correct interpretation of test results.
Sample Storage:
Room temperature for up to 24 hours, then refrigerate the whole blood if it is necessary to be held overnight, weekends, or holidays.
Transport Instructions:
Place specimen into zip-lock type bag, seal bag.
Place requisition into outside pocket of bag.
DO NOT FREEZE, protect specimen by wrapping in bubble-wrap or toweling.
Recommend early AM overnight shipping or equivalent if not on courier service.
Ship refrigerated.
CPT Code: