Anti-Müllerian Hormone
Label Mnemonic: AMH
Epic code: LAB7364
Order form: Laboratory Requisition
Supply order: Supply Order Form
Billing: Billing Policies
CPT code: 83520
Collection Medium:
Plasma Separator Tube 4.5 mL
3 mL in light green top tube or TWO Microtainer® devices
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
1 hour (upon receipt in laboratory)
Reference Range:
    Sex / Age              Reference Range

Females / 20 up to 25      1.22-11.7 ng/mL
Females / 25 up to 30      0.890-9.85 ng/mL
Females / 30 up to 35      0.576-8.13 ng/mL
Females / 35 up to 40      0.147-7.49 ng/mL
Females / 40 up to 45      0.030-5.47 ng/mL 
Interpretive Data:
Menopausal women or women with premature ovarian failure of any cause (including after cancer chemotherapy) will generally have very low antimüllerian hormone (AMH), often below the lower detection limit of quantification (0.03 ng/mL). In women with polycystic ovarian syndrome, AMH concentrations may be two- to five-fold higher than age-appropriate reference intervals. Reference ranges for females less than 20 years old have not been established for this assay. AMH concentrations in women typically reach peak values between 18-25 years old.

Reference ranges for males have not been established for this assay. However, AMH concentration in boys up through 12 years old are generally much higher than those found in adult females. In boys with cryptorchidism, a measurable AMH concentration is predictive of undescended tests, while an undetectable value is suggestive of anorchia or functional failure of the abnormally sited gonad.

Test Limitations:
Cetrotide, Ovitrelle, Endometrin, and Follistatin may interfere with this AMH immunoassay. Do not measure AMH within 2 weeks of using these products.

The assay is unaffected by icterus (bilirubin is less than 66 mg/dL), hemolysis (Hb is less than 1,000 mg/dL), lipemia (Intralipid is less than 1000 mg/dL) and biotin is less than 1200 ng/mL. (criterion: recovery within plus or minus 10% of initial value).
Assay updated with increased tolerance to biotin on 2/21/23.

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Electrochemiluminescence Immunoassay (ECLIA)
Sample Processing:
Centrifuge at a speed and time necessary to get barrier separation of plasma/serum and cells within 1 hour of collection. Send specimen in original tube. Do Not transfer to another tube.
Each sample must be labeled with at least TWO full patient identifiers (First/Last Name & DOB are sufficient for non-UIHC affiliated clients) to avoid sample rejection/delays.
Sample Storage:
All sample storage requirements are intended for delivery to UIHC within 24 hours of collection for testing. If samples won't arrive in this time period, please call the UIHC Core Lab for alternative storage/shipping instructions (319-356-3527).
Transport Instructions:
Place labeled specimen into zip-lock type biohazard bag; seal bag.
Place completed requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.
CPT Code:
See Additional Information:
Biotin Interference with Immunoassays