Thyroid Peroxidase Antibody
Label Mnemonic: | TPOAB |
Epic code: | LAB957 |
Supply order: | Supply Order Form |
Billing: | Billing Policies |
CPT code: | 86376 |
Specimen(s):
Plasma
Collection Medium:
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Plasma Separator Tube 4.5 mL |
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection
containers.
Minimum:
3 mL; plasma separator tube top or TWO Microtainer®
devices.
Turn Around Time:
1 hour (upon receipt in laboratory)
Reference Range:
0.0 - 9.0 IU/mL
Comments:
This assay may be significantly impacted by high-dose biotin
(>5 mg dose) taken within previous 12 hours. High
concentrations of biotin may lead to falsely increased results.
These concentrations may be found in patients taking
over-the-counter supplements with biotin content much higher than
nutritional requirements for biotin. Specimens should not be
collected until at least 12 hours after the last dose.
Test Limitations:
Hemolysis: No significant interference up to an H index of 1500.
Lipemia: No significant interference up to an L index of 2100.
Icterus: No significant interference up to an I index of 66.
Lipemia: No significant interference up to an L index of 2100.
Icterus: No significant interference up to an I index of 66.
Methodology:
Electrochemiluminescence Immunoassay
Sample Processing:
Centrifuge at a speed and time necessary to get barrier separation
of plasma/serum and cells within 1 hour of collection. Send specimen
in original tube. Do Not transfer to another tube.
Each sample must be labeled with at least TWO full patient identifiers (First/Last Name & DOB are sufficient for non-UIHC affiliated clients) to avoid sample rejection/delays.
Each sample must be labeled with at least TWO full patient identifiers (First/Last Name & DOB are sufficient for non-UIHC affiliated clients) to avoid sample rejection/delays.
Sample Storage:
Refrigerate.
Transport Instructions:
Place labeled specimen into zip-lock type biohazard bag; seal
bag.
Place completed requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.
Place completed requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.
See Additional Information:
Biotin Interference with Immunoassays
Biotin Interference with Immunoassays