Thyroid Peroxidase Antibody
Label Mnemonic: TPOAB
Epic code: LAB957
Supply order: Supply Order Form
Billing: Billing Policies
CPT code: 86376
Specimen(s):
Plasma
Collection Medium:
Plasma Separator Tube 4.5 mL
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
3 mL; plasma separator tube top or TWO Microtainer® devices.
Turn Around Time:
1 hour (upon receipt in laboratory)
Reference Range:
0.0 - 9.0 IU/mL
Comments:
This assay may be significantly impacted by high-dose biotin (>5 mg dose) taken within previous 12 hours. High concentrations of biotin may lead to falsely increased results. These concentrations may be found in patients taking over-the-counter supplements with biotin content much higher than nutritional requirements for biotin. Specimens should not be collected until at least 12 hours after the last dose.
Test Limitations:
Hemolysis: No significant interference up to an H index of 1500.
Lipemia: No significant interference up to an L index of 2100.
Icterus: No significant interference up to an I index of 66.
Methodology:
Electrochemiluminescence Immunoassay
Sample Processing:
Centrifuge at a speed and time necessary to get barrier separation of plasma/serum and cells within 1 hour of collection. Send specimen in original tube. Do Not transfer to another tube.
Each sample must be labeled with at least TWO full patient identifiers (First/Last Name & DOB are sufficient for non-UIHC affiliated clients) to avoid sample rejection/delays.
Sample Storage:
Refrigerate.
Transport Instructions:
Place labeled specimen into zip-lock type biohazard bag; seal bag.
Place completed requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.
CPT Code:
86376
 
See Additional Information:
Biotin Interference with Immunoassays