Fluorescence In-Situ Hybridization (FISH-Microdeletion)
| Order form: | Constitutional Genetics Pre and Post-Natal Requisition |
| Supply order: | Supply Order Form |
| Billing: | Billing Policies |
| CPT code: |
88271 x # of probes 88273 x # of probes, 88291 |
Specimen(s):
Peripheral Blood, Fibroblasts, Other Tissue (fibroblasts, and OT
need to establish cultures first, not going to meet 5-7 day TAT)
Collection Medium:
|
| Green top tube 10 mL (Na Heparin) Hospital Stores #907693 |
Minimum:
5-10 cc adult, 2 cc infants of venous blood collected in a green-top
Vacutainer® with sodium heparin. Invert tube to mix well.
Label the tube with patient name and medical record number. DO NOT
FREEZE OR CENTRIFUGE.
Testing Schedule:
Specimens accepted in the lab Monday-Friday, 0800-1700.
Turn Around Time:
Allow 5-7 days for final results.
Reference Range:
Varies for each probe (set). Unique sequence probes labeled with
fluorochrome. Contact lab for details.
Comments:
Epic code: CYT54
This test can be used as an adjunct to chromosomal analysis for detection of submicroscopic/cryptic rearrangements in certain congenital disorders. Suitable for metaphase analysis only.
Probes currently available include:
1p36
Angelman syndrome
Cri-du-chat
Deletion 22q syndromes
Langergied
Miller-Dieker syndrome
Prader-Willi syndrome
Smith-Magenis syndrome
SRY(Yp11.3)
STS[del(Xp22.3)]
Williams syndrome
Wolf-Hirschhorn syndrome
Shivanand R. Patil Cytogenetics & Molecular Laboratory Website
This test can be used as an adjunct to chromosomal analysis for detection of submicroscopic/cryptic rearrangements in certain congenital disorders. Suitable for metaphase analysis only.
Probes currently available include:
1p36
Angelman syndrome
Cri-du-chat
Deletion 22q syndromes
Langergied
Miller-Dieker syndrome
Prader-Willi syndrome
Smith-Magenis syndrome
SRY(Yp11.3)
STS[del(Xp22.3)]
Williams syndrome
Wolf-Hirschhorn syndrome
Shivanand R. Patil Cytogenetics & Molecular Laboratory Website
Methodology:
Fluorescence In-Situ Hybridization (FISH)
Instructions:
Provide details of clinical information. If a specimen is collected over the weekend, please call (319) 356-1616 and ask the operator to page the cytogenetics on-call staff at pager #5525. For billing and/or shipping questions, contact University of Iowa Diagnostic Laboratories at 1-866-844-2522 (toll free) or 319-384-7213 (Fax).
Sample Processing:
Do Not Centrifuge.
Relevant clinical information must be submitted with specimen in order to provide correct interpretation of test results.
Relevant clinical information must be submitted with specimen in order to provide correct interpretation of test results.
Sample Storage:
Specimen cannot be frozen.
Transport Instructions:
Place specimen into zip-lock type bag, seal bag.
Ship at room temperature.
Ship at room temperature.