Urine Myoglobin Assay Now Performed in Core Laboratory

Effective today, October 1, 2014, the University of Iowa Hospitals and Clinics core clinical chemistry laboratory will be performing urine myoglobin assay in-house.  This was previously sent out to reference laboratory.

Units of Measurement ng/mL
Collection Medium Clear top tube
Delivery to 6240 RCP Deliver to laboratory immediately after collection
Reference Range < 21 ng/mL
Test availability 24 hours/day, 7 days a week (including holidays)
Turnaround Time 1 hour or less upon receipt in the laboratory
Result Parameters Results up to 10,000 ng/mL may be seen with mild muscle injury, strenuous exercise, and myocardial infarction.  Patients with urine myoglobin exceeding 10,000 ng/mL are at risk of acute renal failure.  Renal toxicity depends on multiple factors such as renal perfusion rate and degree of urine acidity.  Elevated urine excretion of myoglobin is not specific for a clinical disorder.

Questions should be directed to Matthew Krasowski, MD, PhD, medical director of the Clinical Chemistry Laboratory (384-9380, matthew-krasowski@uiowa.edu).