Unavailability of Plasma Ketones Assay

Effective Monday, November 14, 2011, the University of Iowa Hospitals and Clinics core clinical laboratory will have to discontinue the laboratory test "KETONES" (LAB44). This laboratory test is a semi-quantitative assay for plasma ketones that uses the Bayer Acetest tablets. This laboratory reagent is currently unavailable nationally for an indefinite period of time.

There are a number of alternative tests that are useful in the workup of diabetic ketoacidosis and other ketotic states:

"B-HYDROXYBUTYRATE" [LAB570] – quantitative assay for plasma beta-hydroxybutyrate

"URINALYSIS" [LAB1160] – includes semi-quantitative assay for urine ketones

"BASIC METABOLIC PANEL" [LAB15] which would generate "ELECTROLYTE BALANCE" (anion gap)



Questions should be directed to Matthew Krasowski, MD, PhD, medical director of the Clinical Chemistry (384–9380, matthew-krasowski@uiowa.edu).