Quantitative (viral load) Testing for Cytomegalovirus (CMV) Infection
The Molecular Pathology Laboratory in the Department of Pathology is now providing quantitative (viral load) testing for cytomegalovirus (CMV) infection. A quantitative PCR based assay (real-time PCR) has been validated on plasma and cerebrospinal fluid (CSF) specimens. The linear range of detection is 200 to 2.0 million copy/ml. Specimens that have detectable CMV less than 200 copy/ml will be reported as indeterminate.
Comparison of results with concurrent CMV Antigen Detection results demonstrated a relative correlation of 200 to 3000 copy/ml at low antigenemia results of approximately 10/300,000 white cells and 80,000 to 1.6 million copy/ml at the high antigenemia results of >200 positive white cells.
Please use Order Form: A-1A Pathology Doctor’s Order Miscellaneous Request, until further notice.
Acceptable Specimens: plasma and CSF
Collection Medium: Lavender top tube (EDTA) or CSF collection container.
Deliver to Lab within 4 hours of draw.
Specimens received by 1 pm Monday, Wednesday and Friday will be tested that afternoon and reported the next morning.
Linear range of Detection: 200 copy/ml to 2 million copy/ml
Results reported: Negative
Indeterminate, <200 copy/ml
Quantitative value, 200 - 2,000,000 copy/ml
Positive, >2,000,000 copy/ml
Inconclusive, please submit an additional specimen for testing.
Questions and comments concerning the test can be directed to Aaron Bossler, M.D., Ph.D. Tel: 384-9566 or by e-mail at firstname.lastname@example.org.