- Soluble Transferrin Receptor assay (STFR) Testing
On Monday, December 17, 2001, the Clinical Chemistry Laboratory of the Department of Pathology will begin accepting specimens for the Soluble Transferrin Receptor assay (STFR). STFR is useful in distinguishing anemia of chronic disease from iron deficiency. The STFR will be increased in iron deficiency. Unlike ferritin, STFR is not an acute phase reactant and is not influenced by inflammation. STFR is also not influenced by acute liver disease or malignancy. In addition to iron deficiency elevated STFR values are also found in polycythemia, hemolytic anemia, thalassemia, hereditary spherocytoses, sickle cell anemia, megaloblastic anemia due to vitamin B12 and folate deficiency, and myelodysplastic syndromes.
Initially the assay will be run on Tuesday and Thursday afternoons. There is an 11:00 AM cutoff for samples. Increased service will be provided if demand warrants. Acceptable samples are a speckled top SST Vacutainer or one yellow top microtube. Reference ranges are; males: 2.2-4.5 mg/L and females: 1.8-4.6 mg/L. Values tend to be higher in infants and children. To order, use a miscellaneous requisition and write soluble transferrin receptor or STFR. Deliver to Specimen Control, 6240 RCP The charge for the test is $43.00. Questions can be directed to Ronald Feld, Ph.D. at 356-1759.
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