Beginning Monday, March 13, 2000 at 7:00 a.m., the Clinical Chemistry Laboratory of the Department of Pathology will institute a new testing platform for cardiac markers. The following markers will be offered CK-MB and Troponin T. The CK-MB test is equivalent to the previous test in terms of sensitivity and specificity except for a change in decision level. The new decision levels for CK-MB are greater than 7.5 ng/mL when the total CK is within the reference range and greater than 2.5 for an index when the total CK is outside the reference range.
Troponin T is equivalent to Troponin I in terms of sensitivity and specificity in detecting cardiac lesions (see ref.). A level of Troponin T greater than 0.1 ng/mL is considered significant.
Sample volumes and tube types remain the same. Pathology requisitions will be revised in the future to reflect this change. For now, an order for Troponin I received after March 13th will receive a Troponin T. Questions may be directed to Dr. Ronald Feld at 61759.
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