Effective today, May 23, 2017, the University of Iowa Hospitals and Clinics (UIHC) Clinical Chemistry laboratory changed the age- and gender-specific reference ranges for ALKALINE PHOSPHATASE (LAB112).  This updates pediatric ranges to newly validated and standardized values.  Adult reference ranges are unchanged.

The new reference values are summarized in the table:

Age	Male reference range (U/L)	Female reference range (U/L)
0 -14 days	83 - 248	83 - 248
15 days - 12 months old	122 - 469	122 - 469
1 - 9 years	142 - 335	142 - 335
10 - 12 years	129 - 417	129 - 417
13 - 14 years	116 - 468	57 - 254
15 - 16 years	82 - 331	50 - 117
17 - 18 years	55 - 149	45 - 87
19+ years [unchanged]	40 - 129	35 - 104

Questions should be directed to Matthew Krasowski, MD, PhD, medical director of the Clinical Chemistry (384-9380, matthew-krasowski@uiowa.edu).