New Endocrine Assays (ACTH, HGH, PTH, DHEA-S, Thyroglobulin Antibody- TgAb)

Beginning Monday, February 19, 2001, the Clinical Chemistry laboratory of the Department of Pathology will begin using a new immunoassay analyzer (Nichols Advantage). New reference ranges will be implemented for the following analytes:

Age Group
Old Range
New Range
DHEA-S FEMALES





MALES		 20-29
30-39
40-49
50-59
>60

20-29
30-39
40-49
50-59
>60
 410-4470 ng/mL
160-3040 ng/mL
360-2730 ng/mL
330-2520 ng/mL
120-1420 ng/mL

1080-6950 ng/mL
770-5280 ng/mL
960-4740 ng/mL
330-2940 ng/mL
170-1750 ng/mL 		620-6150 ng/mL
520-4000 ng/mL
440-3520 ng/mL
390-1830 ng/mL
110-1500 ng/mL

1020-5970 ng/mL
1090-6660 ng/mL
500-5170 ng/mL
630-4440 ng/mL
320-1540 ng/mL
ACTH 7-51 pg/mL 9-52 pg/mL
HGH FEMALES
MALES		 <5 ng/mL
<5 ng/mL 		< = 14.7 ng/mL
< = 0.51 ng/mL
Due to pulsatile secretion, a single measurement may be misinterpreted. For a provocative tests, a cutoff of 7 ng/mL is suggested.
Intact PTH 10-65 pg/mL 10-65 pg/mL
TgAb <2.0 IU/mL <2.0 IU/mL

Reference ranges for Intact PTH and thyroglobulin antibodies (TgAb) do not change.

Sample requirements do not change and the assays will be run on Tuesday and Thursday with an 8 a.m. sample cut off. Questions can be directed to Ronald Feld at 6-1759.