Hepatitis A Antibody (G & M)
Label Mnemonic: HAVAB
Epic Lab Code: LAB620
Downtime Form: A-1a General Laboratory Requisition
Chemistry
6240 RCP
356-3527
Specimen(s):
Plasma
Collection Medium:
Plasma Separator Tube 4.5 mL
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
3 mL whole blood from light green top tube or TWO Microtainer® devices for pediatric patients.
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
1 hour (upon receipt in laboratory)
Reference Range:
Negative
Interpretive Data:
The cutoff is set according to the WHO recommendation for vaccination. Results obtained with the Elecsys Anti-HAV assay are resulted as follows: Negative <18.0 IU/L Grayzone ≥18.0 <22.0 IU/L Positive ≥22.0 IU/L If clinically indicated, patients who have samples that are resulted as "Grayzone" should be re-tested in approximately two weeks.
Test Limitations:
The assay is unaffected by icterus (bilirubin < 855 μmol/L or < 50 mg/dL), hemolysis (< 1000 mg/dL), lipemia (Intralipid < 1500 mg/dL), and biotin < 205 nmol/L or < 50 ng/mL.

In patients receiving therapy with high biotin doses (i.e. > 5 mg/day), no sample should be taken until at least 8 hours after the last biotin administration.

As with all tests containing monoclonal mouse antibodies, erroneous findings may be obtained from samples taken from patients who have been treated with monoclonal mouse antibodies or have received them for diagnostic purposes. In rare cases, interference due to extremely high titers of antibodies to analyte-specific antibodies, streptavidin or ruthenium can occur. These effects are minimized by suitable test design.
Methodology:
Electrochemiluminescence Immunoassay
CPT Code:
86708