Prostate-Specific Antigen (PSA), Screening

Label Mnemonic:	PSAS
Epic code:	LAB670
Downtime form:	A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Chemistry
6240 RCP
356-3527

Specimen(s):

Plasma

Collection Medium:

Plasma Separator Tube 4.5 mL

Alternate Collection Media:

Call laboratory for additional acceptable specimen collection containers.

Minimum:

3 mL whole blood in light green top or TWO Microtainer^® devices.

Testing Schedule:

24 hrs/day, 7 days a week, including holidays.

Turn Around Time:

1 hour (upon receipt in laboratory)

Reference Range:

   Age     Reference Range
Up to 50   0.00-2.50 ng/mL
50 - 59    0.00-3.50 ng/mL
60 - 69    0.00-4.50 ng/mL
> 70       0.00-6.50 ng/mL

Age specific normal values from the literature for PSA are provided as 
a guide only.  No one decision level is appropriate when utilizing PSA 
in screening situation.  Age, family history, previous values, and 
other factors should be used in decisions involving PSA values.

Comments:

Assay updated with increased tolerance to biotin on 11/9/21.

See: "PSA, Total" to order monitoring PSA test. PSA measurement used in conjunction with DRE (digital rectal exam) is indicated as an aid for the detection of prostate cancer in men aged 50 years or older, must be identified as PSA for screening. It is also useful in monitoring patients with known prostate cancer. PSA is specific to the prostate gland and is present in normal, hyperplastic and neoplastic prostatic epithelium. Plasma elevations are detected in not only prostate carcinoma, but also in benign prostatic hypertrophy and inflammatory conditions of the prostate and adjacent genitourinary tissues. Diagnosis of prostate cancer requires biopsy and histopathologic examination.

Methodology:

Electrochemiluminescence Immunoassay

CPT Code:

CPT codes: G0103, 84153

See also:
Prostate-Specific Antigen (PSA), Total, Plasma