Alpha-1-Antitrypsin
Label Mnemonic: A1AC
Epic Lab Code: LAB2565
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Blood and 24 hr stool
Collection Medium:
and
Red top tube 5 mL (Clot Activator) 24, 48, 72 hour fecal specimen, stool container(s)
Minimum:
24 hr fecal collection and 1.0 mL serum from red top or serum gel tube.
Rejection Criteria:
Specimens other than stool plus serum.
Delivery Instructions:
Submit specimen to laboratory as soon as possible after collection period is completed.
Turn Around Time:
2 working days upon receipt at reference laboratory
Reference Range:
Clearance: < or = 27 mL/24 hours
Fecal alpha-1-antitrypsin concentration: < or = 54 mg/dL
Serum alpha-1-antitrypsin concentration: 100 - 190 mg/dL
Comments:
Fecal specimen must be collected in special containers available from Mailouts at 356-8395 Monday-Friday, or Specimen Control (6240 RCP) at 356-3527. Draw serum sample during stool collection period. If no fecal specimen obtained in 24 hours, extend collection to 48-72 hours and note time frame on requisition. In the absence of either a 24-hour stool collection or a contemporary serum specimen, the fecal concentration of alpha-1-antitrypsin (A1A) can be used as a surrogate marker. The clearance is preferred in order to normalize the large range of serum A1A concentrations and the variability in random stool A1A concentration.
Methodology:
Nephelometry
CPT Code:
82103