Felbamate Drug Level
Label Mnemonic: FBM
Epic code: LAB3125
Downtime form: A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Commercial Mailout Laboratory
6240-8 RCP
356-8593
Specimen(s):
Serum
Specimen Instructions:
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.
Collection Medium:
Red top tube 5 mL (Clot Activator)
Alternate Collection Media:
Green top tube 4 mL (Na Heparin) or Lavender top tube 3 mL (EDTA) or Pink top tube 6 mL (K2-EDTA)
Minimum:
Adult and Pediatrics Preferred Minimum: 1.0 mL serum
Adult and Pediatrics Absolute Minimum: 0.5 mL serum
Rejection Criteria:
Gel separator tubes
Turn Around Time:
1 week upon receipt at reference laboratory
Reference Range:
Therapeutic Range: 30-60 μg/mL
Toxic Level: Greater than or equal to 100 µg/mL
Test Limitations:
The proposed therapeutic range for seizure control is 30-60 µg/mL. Pharmacokinetics varies widely, particularly with co-medications, age, and/or compromised renal function. No critical value has been defined.
Methodology:
High Performance Liquid Chromatography (HPLC)
CPT Code:
80167